The ocimum genome
Ajit Kumar Shasany (Editor), Chittaranjan Kole (Editor)
This book provides an overview of the Ocimum genus from its genetic diversity to genome sequences, metabolites and their therapeutic utilities. Tulasi, Ocimum tenuiflorum, as a member of the family Lamiaceae, is a sacred plant in India. The plants of this genus Ocimum are collectively referred to as Basil and holy basil is worshipped in the Hindu religion. Basils are reservoirs of diverse terpenoids, phenylpropanoids and flavonoids, in addition to commercially important aromatic essential oils. In 2016, two working groups in India published the genome sequence in two different genotypes of Ocimum tenuiflorum. To help the readers understand the complexities of the genus and different chemotypes, this book accumulates all the available information on this medicinal plant including the genome. The complete knowledge may enable researchers to generate specific chemotypes in basil either through conventional breeding or development of transgenic lines. It also makes it possible to investigate the medicinal nature of holy basil compared to different species of the same genus
1 online resource : illustrations (some color)
9783319974309, 9783319974316, 3319974300, 3319974319
1056109188
Intro; Foreword; Preface to the Series; Preface; Contents; 1 Ocimum as a Promising Commercial Crop; Abstract; 1.1 Cultivation Technology; 1.2 Common Varieties; 1.3 Soil and Climate; 1.4 Land Preparation; 1.5 Propagation; 1.5.1 Raising of Nursery; 1.5.2 Transplanting; 1.5.3 Direct Sowing; 1.5.4 Irrigation; 1.6 Interculture and Weeding; 1.7 Manures and Fertilizers; 1.8 Pest and Diseases; 1.9 Crop Rotation; 1.10 Harvesting; 1.11 Distillation and Oil Yield; 1.12 Uses of Basil Oil; References; 2 Ocimum Species: A Longevity Elixir; Abstract; 2.1 Aging; 2.2 Theory of Aging. 2.3 C. elegans as a Model for Antiaging Studies2.4 Medicinal Plants and Aging; 2.5 Ocimum spp; 2.6 Phytoconstituents of Ocimum spp; 2.7 Ocimum sps: The Elixir of Life; References; 3 Ocimum: The Holy Basil Against Cardiac Anomalies; Abstract; 3.1 Introduction; 3.2 Types of Cardiovascular Diseases; 3.2.1 Hypertension; 3.2.2 Aortic Aneurysm/Abdominal Aortic Aneurysm; 3.2.3 Acute Coronary Syndrome; 3.2.4 Angina Pectoris; 3.2.5 Atherosclerosis; 3.2.6 Coronary Heart Disease (CHD)/Coronary Artery Disease (CAD); 3.2.7 Heart Attack/Acute Myocardial Infarction (AMI); 3.2.8 Congestive Heart Failure. 3.2.9 Ischemic Heart Disease (IHD)3.2.10 Ischemic Stroke; 3.3 Plants as a Medicine; 3.3.1 Ocimum (Tulsi); 3.3.2 Systematics of Tulsi; 3.3.3 Phytochemical Constituents; 3.3.4 Antihypertensive Properties; 3.3.5 Effect on Ischemia; 3.3.6 Effect on Pulmonary Hypertension; 3.3.7 Lipid-Lowering Properties of Ocimum; 3.3.8 Antiplatelet Aggregation Activity; 3.3.9 Antioxidant and Antidiabetic Properties; 3.4 Summary; References; 4 Evolutionary Analysis of a Few Protein Superfamilies in Ocimum tenuiflorum; Abstract; 4.1 Introduction; 4.1.1 Biosynthesis of Terpenoids; 4.1.2 Terpene Synthases. 4.1.3 Cytochrome P4504.1.4 Rhomboid Proteases; 4.2 Materials and Methods; 4.2.1 Sequence Search Methodology for Collecting TPS and CYP450 in the Ocimum tenuiflorum (Ote) Proteome; 4.2.2 Structural Alignment to Compare the Functional Important Residues; 4.2.3 Phylogenetic Analysis of TPS and CYP450; 4.2.4 Identification of Rhomboid Proteases in the Ote Proteome; 4.2.5 Identification of Transmembrane Helices and Subcellular Locations of the Rhomboid Proteins; 4.2.6 Multiple Sequence Alignment, Phylogeny and Identification of Variants in Functionally Important Residues. 4.2.7 Prediction of Domain Architecture4.3 Results and Discussion; 4.3.1 Sequence and Structure-Based Analysis of Newly Identified Ote (TPS); 4.3.2 Sequence and Structure Analysis of CYP450; 4.3.3 Domain Architecture Analysis of Ote Rhomboid Hits; 4.3.4 Predicting the Cellular Localization, Function, and TM-Helices of Ote Rhomboid Hits; 4.3.5 Alignment to Identify Functionally Important Residues; 4.3.6 Phylogeny and Orthology with Other Plant Hits; 4.3.6.1 Class I-All the Functional Residues Are Conserved; 4.3.6.2 Class II-Only GXSX Conserved; 4.3.6.3 Class III-I Rhom-like Class